The 41-kilometre walk is organised by Ross Steele in memory of his stepfather who succumbed to the disease.
The 20 expected participants will hike from The Pyg in Clausen to Mersch and back in kilts, although some have chosen to complete only half of the walk.
According to Steele, organisation has been difficult this year due to the coronavirus pandemic, and some Scots who had been keen to join have been unable to make it. Steele's sister is organising a similar event in Scotland instead.
Afterwards, participants and friends will enjoy drinks, a quiz and a raffle at the Pyg, although coronavirus restrictions will be respected.
Steele is hoping to match last year's total of €3,000 in aid of Pancreatic Cancer Scotland. You can contribute to his JustGiving page here.
