The United States and Iran escalated their conflict, with both sides accused of hitting infrastructure used by civilian populations.
Iran said American strikes hit bridges, transport hubs and energy facilities, while Tehran lashed out at US-allied Mideast countries.
At the same time, shipping through the vital Strait of Hormuz was all but stalled.
Here are the latest developments on Friday:
UN chief Antonio Guterres called attacks on civilian infrastructure in Iran and elsewhere in the region "unacceptable".
Iranian state media reported at least eight people killed and 20 wounded in US attacks.
Iranian authorities urged citizens to cut back on electricity use, including air conditioners, after saying the grid was under strain from US strikes on power facilities.
Kuwait reported an Iranian attack on a power and water plant, and said seven of its military personnel had been wounded in a drone attack on army facilities.
Bahrain and Qatar also said they had intercepted missiles.
The virtual closure of the Strait of Hormuz sent oil higher, with Brent crude back above $86 a barrel.
"The ongoing conflict, combined with threats to major shipping routes such as the Strait of Hormuz and potentially the Red Sea, has increased uncertainty across global financial markets," said Trade Nation analyst David Morrison.
Drone and rocket strikes killed nine members of an Iranian Kurdish armed opposition group in Iraq's Kurdistan region, the exiled party said, blaming the attack on Iran.
Tehran will not halt its attacks in the region until the US stops striking Iran's southern coastline and the Strait of Hormuz, the commander of the Aerospace Force in Iran's Revolutionary Guards, Majid Mousavi, vowed in a social media post.
A Syrian military source denied to AFP that Iran had bombed the Al-Tanf base near Syria's southeastern borders with Jordan and Iraq, after Tehran's Revolutionary Guards said they had targeted the facility in response to US strikes.
A tanker was hit overnight by an "unknown projectile" off the coast of Oman, the UK Maritime Trade Operations agency said, as Iran and the United States exchanged fire over control of the Strait of Hormuz.
The tanker sustained "minor structural damage", but all crew were safe, the agency added.
China's and Pakistan's foreign ministers called on the United States and Iran to end fighting and return to the negotiating table, after meeting in Shanghai.
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