Two pandas at a zoo in central France are to return to China on Tuesday after the female was diagnosed with kidney failure, drawing hundreds of visitors for a final goodbye.

Huan Huan and her partner Yuan Zi arrived at the Beauval Zoo in 2012 as part of China's "panda diplomacy" programme, which sees the black-and-white bears dispatched across the globe as soft-power ambassadors.

The two pandas, both 17, were meant to stay in France until January 2027, but will return to China on Tuesday to live out their retirement at the Chengdu panda sanctuary, leaving behind some devoted fans.

More than 200 well-wishers braved a cold and rainy Sunday to say "bon voyage", including one couple dressed head-to-toe in panda-themed gear, who say they have visited the bears "more than a thousand times" since their arrival in 2012.

Patrice Colombel, an electronics technician, and his wife Veronique, an administrative assistant at a secondary school, told AFP they would not have missed the chance to see them off.

"They are the first pandas we have ever known. We wanted to be there to say goodbye to them," the couple visiting from the southwest city of Bordeaux told AFP.

Huan Huan and Yuan Zi will be escorted to Paris-Charles de Gaulle airport under heavy police protection for their 12:30 pm (1130 GMT) flight on Tuesday.

-'Engraved in our hearts'-

The pair produced three cubs while in France -- the first pandas to do so in the country -- and became star attractions at the Beauval zoo in Saint-Aignan-sur-Cher, which welcomed some two million visitors in 2023.

RTL

Huan Dudu was one of three siblings to be born in France / © AFP

The decision to send them back to China came after Huan Huan was diagnosed with chronic kidney disease -- a common condition in bears around her age, according to zoo director Rodolphe Delord.

The move came with "a twinge of sadness", Delord said.

But the twins born in 2021 are expected to remain at Beauval for now, said Delord, adding he hopes to extend the zoo's partnership with China beyond 2027.

The eldest of the offspring, Yuan Meng, left France for his ancestral China in 2023.

For panda keeper Delphine Pouvreau, their departure will be "very hard" for the caretakers, who have forged a strong bond with the bears.

"We experienced the first birth of a baby panda in France here," she said.

"This memory will remain engraved in our hearts."

The giant panda was downgraded last year from "endangered" to "vulnerable" on the global list of at-risk species.

Only about 20 zoos outside China have pandas, which have become a symbol of Beijing's diplomatic friendships.

China has been using so-called "panda diplomacy", in which the bears are sent across the globe as soft-power ambassadors, for decades. In 1972, it gifted a pair of pandas to Washington, following US president Richard Nixon's historic visit to the Communist nation.